Interactor 1: FGF2 (P09038)
Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2)
Gene: FGF2

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 19422911, 24509440
Identification Methods far western blotting, enzyme linked immunosorbent assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set, FGF~Ig_3
Common GO terms GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0030154 - cell differentiation
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 288
Hs

1 4391
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024