HitPredict

Interactor 1: ITB1 (P09055)
Integrin beta-1 (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29)
Gene: Itgb1

Interactor 2: ITA3 (Q62470)
Integrin alpha-3 (CD49 antigen-like family member C) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]
Gene: Itga3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25808491, 10939329, 15181153
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, I-EGF_1~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, FG-GAP~Integrin_beta, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin
Common GO terms GO:0001968 - fibronectin binding
GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005518 - collagen binding
GO:0005886 - plasma membrane
and 25 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 798
Mm

1 1053
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Last updated: 15 Jul 2024