HitPredict

Interactor 1: HXB5 (P09067)
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)
Gene: HOXB5

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 536
+	Hs
		433220 HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		411952 HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		522809 HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		412230 Q6FHY5_HUMAN (10-264): 3.75e-30: 116: 22.66		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		412045 HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		412088 MEOX2_HUMAN (10-264): 7.22e-30: 115: 22.18		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		412044 HXA9_HUMAN (1-256): 8.04e-30: 114: 24.43		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		433532 HXB5_HUMAN (1-269): 1.85e-52: 173: 100.00		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		433531 HXC4_HUMAN (66-266): 1.77e-43: 150: 37.74		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		337365 HXC8_HUMAN (1-262): 2.58e-30: 115: 28.30		ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00
+	Hs
		837944 MEOX2_HUMAN (10-264): 7.22e-30: 115: 22.18		BTK_HUMAN (43-527): 1.18e-154: 458: 34.35