Interactor 1: HXB5 (P09067)
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)
Gene: HOXB5

Interactor 2: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 269
Hs

1 747
+ Hs
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+ Mm
+ Dm
+ Dm
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024