HitPredict

Interactor 1: SCR (P09077)
Homeotic protein Sex combs reduced
Gene: SCR

Interactor 2: SLOU (P22807)
Homeobox protein slou (Homeobox protein NK-1) (Protein slouch) (S59/2)
Gene: SLOU

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	25869471
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 417 Dm			1 659
+	Dm
		367176 ANTP_DROME (95-404): 6.77e-36: 137: 36.05		SLOU_DROME (1-659): 1.84e-165: 491: 100.00
+	Dm
		447311 SCR_DROME (1-417): 2.07e-59: 201: 100.00		SCR_DROME (501-622): 7.31e-30: 124: 29.71
+	Hs
		658622 MSX1_HUMAN (211-398): 2.04e-44: 158: 26.73		MSX2_HUMAN (541-655): 1.73e-33: 131: 38.46
+	Hs
		620232 MSX1_HUMAN (211-398): 2.04e-44: 158: 26.73		PAX3_HUMAN (471-655): 7.88e-31: 128: 22.73
+	Dm
		447318 TIN_DROME (93-403): 2.42e-41: 153: 19.20		SCR_DROME (501-622): 7.31e-30: 124: 29.71
+	Hs
		656395 MSX2_HUMAN (213-400): 5.58e-37: 137: 26.84		PIT1_HUMAN (344-610): 6.48e-35: 135: 15.33
+	Hs
		724174 MSX2_HUMAN (213-400): 5.58e-37: 137: 26.84		MSX2_HUMAN (541-655): 1.73e-33: 131: 38.46
+	Hs
		678782 HXD3_HUMAN (156-401): 2.7e-35: 136: 28.57		ALX4_HUMAN (344-658): 2.86e-31: 128: 17.07
+	Hs
		446885 HXB5_HUMAN (179-395): 2.73e-34: 130: 33.64		HXC4_HUMAN (534-641): 1.7e-34: 133: 37.04
+	Hs
		620235 MEOX1_HUMAN (225-398): 1.34e-35: 133: 31.61		PAX3_HUMAN (471-655): 7.88e-31: 128: 22.73
+	Hs
		568043 HXB6_HUMAN (198-393): 3.41e-35: 131: 38.27		ALX4_HUMAN (344-658): 2.86e-31: 128: 17.07
+	Hs
		538750 HXB1_HUMAN (160-406): 1.44e-35: 134: 27.80		HXA1_HUMAN (375-620): 4.82e-30: 123: 22.76
+	Hs
		858079 GBX2_HUMAN (153-416): 6.1e-34: 131: 25.56		GBX1_HUMAN (479-615): 7.78e-31: 126: 33.57
+	Hs
		446864 HXD4_HUMAN (205-389): 8.42e-36: 133: 41.71		HXA5_HUMAN (385-617): 6.76e-31: 123: 21.25
+	Mm
		192297 HXC4_MOUSE (188-400): 1.72e-33: 128: 34.86		ALX4_MOUSE (358-658): 5.39e-31: 127: 15.61
+	Hs
		837783 MEOX1_HUMAN (225-398): 1.34e-35: 133: 31.61		MEOX2_HUMAN (509-608): 1.46e-29: 121: 40.39
+	Mm
		192284 HXA11_MOUSE (71-394): 6.91e-32: 125: 16.67		ALX4_MOUSE (358-658): 5.39e-31: 127: 15.61
+	Hs
		447232 HXB5_HUMAN (179-395): 2.73e-34: 130: 33.64		MEOX2_HUMAN (509-608): 1.46e-29: 121: 40.39
+	Hs
		447257 HXB5_HUMAN (179-395): 2.73e-34: 130: 33.64		Q6FHY5_HUMAN (509-608): 1.43e-29: 121: 40.39
+	Dm
		1229480 Q9VSC2_DROME (77-387): 6.98e-41: 153: 21.34		Q8MZ02_DROME (505-603): 5.94e-12: 69.7: 45.46