HitPredict

Interactor 1: BCD (P09081)
Homeotic protein bicoid (PRD-4)
Gene: BCD

Interactor 2: UBX (P83949)
Homeotic protein ultrabithorax
Gene: UBX

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0043565 - sequence-specific DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Dm			1 389
+	Dm
		447348 BCD_DROME (1-494): 3.59e-141: 416: 100.00		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		428853 BCD_DROME (1-494): 3.59e-141: 416: 100.00		DFD_DROME (296-369): 8.95e-20: 92.8: 63.51
+	Dm
		367219 FTZ_DROME (49-296): 4.02e-37: 143: 23.60		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		447432 GSBN_DROME (43-357): 3.27e-37: 143: 18.30		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Hs
		620134 PAX7_HUMAN (80-348): 1.83e-41: 157: 16.90		MNX1_HUMAN (197-387): 6.03e-52: 179: 33.67
+	Dm
		447431 GSBN_DROME (43-357): 3.27e-37: 143: 18.30		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		415559 PRD_DROME (36-349): 1.08e-33: 136: 13.57		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Hs
		620236 PAX3_HUMAN (55-338): 6.8e-44: 163: 18.15		MEOX2_HUMAN (114-366): 8.49e-34: 129: 20.16
+	Mm
		623693 PAX3_MOUSE (55-338): 4.75e-43: 160: 18.48		MEOX1_MOUSE (149-378): 2.72e-32: 123: 18.93
+	Mm
		623694 PAX3_MOUSE (55-338): 4.75e-43: 160: 18.48		MEOX2_MOUSE (114-366): 8.16e-32: 123: 19.76
+	Hs
		678782 ALX4_HUMAN (14-279): 5.69e-37: 142: 16.25		HXD3_HUMAN (213-387): 2.01e-35: 136: 33.14
+	Hs
		1077278 ALX4_HUMAN (14-279): 5.69e-37: 142: 16.25		ALX1_HUMAN (174-386): 3.05e-33: 128: 20.19
+	Mm
		192297 ALX4_MOUSE (14-279): 2.77e-37: 143: 16.25		HXC4_MOUSE (160-389): 4.3e-33: 126: 25.31
+	Hs
		211823 PITX1_HUMAN (40-322): 1.11e-38: 145: 16.78		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Mm
		192280 ALX4_MOUSE (14-279): 2.77e-37: 143: 16.25		HXD12_MOUSE (132-359): 2.35e-32: 124: 26.67
+	Mm
		192296 ALX4_MOUSE (14-279): 2.77e-37: 143: 16.25		CDX4_MOUSE (133-381): 2.02e-32: 124: 22.00
+	Hs
		980974 ALX4_HUMAN (14-279): 5.69e-37: 142: 16.25		EMX1_HUMAN (110-370): 5.74e-32: 124: 17.42
+	Hs
		150341 PITX1_HUMAN (40-322): 1.11e-38: 145: 16.78		CDX4_HUMAN (133-381): 1.03e-30: 120: 19.37
+	Hs
		568043 ALX4_HUMAN (14-279): 5.69e-37: 142: 16.25		HXB6_HUMAN (161-372): 7.83e-31: 119: 31.13
+	Dm
		367210 PRD_DROME (36-349): 1.08e-33: 136: 13.57		FTZ_DROME (296-353): 9.77e-22: 97.8: 79.31