HitPredict

Interactor 1: PO2F2 (P09086)
POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)
Gene: POU2F2

Interactor 2: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16103132
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 479 Hs			1 773
+	Hs
		764630 CUX1_HUMAN (8-440): 1.79e-43: 166: 16.95		TLE4_HUMAN (1-773): 0: 622: 100.00
+	Mm
		631278 PO2F1_MOUSE (58-409): 3.26e-35: 141: 55.46		TLE4_MOUSE (1-773): 0: 623: 99.61
+	Hs
		980662 LHX3_HUMAN (286-470): 2.9e-39: 148: 22.12		TLE1_HUMAN (8-773): 0: 580: 86.27
+	Hs
		980663 HESX1_HUMAN (190-360): 1.48e-33: 126: 23.12		TLE1_HUMAN (8-773): 0: 580: 86.27
+	Hs
		764629 CUX1_HUMAN (8-440): 1.79e-43: 166: 16.95		TLE3_HUMAN (8-773): 0: 539: 80.90
+	Hs
		822627 LHX1_HUMAN (266-465): 3.39e-13: 73: 24.03		TLE1_HUMAN (8-773): 0: 580: 86.27
+	Hs
		839732 LHX2_HUMAN (266-435): 1.17e-12: 71.4: 21.26		TLE1_HUMAN (8-773): 0: 580: 86.27
+	Hs
		980760 ZFHX3_HUMAN (276-362): 3.29e-11: 68.2: 25.29		TLE3_HUMAN (8-773): 0: 539: 80.90
+	Dm
		558391 Q9NHP8_DROME (26-396): 8.87e-43: 160: 13.88		GROU_DROME (8-773): 1.23e-144: 443: 59.14
+	Hs
		993635 LHX3_HUMAN (286-470): 2.9e-39: 148: 22.12		TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68
+	Mm
		631274 PO2F1_MOUSE (58-409): 3.26e-35: 141: 55.46		TLE5_MOUSE (8-205): 3.23e-94: 293: 67.68
+	Hs
		839735 LHX2_HUMAN (266-435): 1.17e-12: 71.4: 21.26		TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68
+	Hs
		993437 ZFHX3_HUMAN (276-362): 3.29e-11: 68.2: 25.29		TLE5_HUMAN (8-205): 3.48e-94: 293: 67.68
+	Mm
		590275 PO5F1_MOUSE (72-422): 5.45e-50: 176: 31.48		WDR5_MOUSE (658-772): 3.81e-36: 141: 21.37
+	Hs
		903141 PO5F1_HUMAN (120-422): 1.27e-45: 164: 32.57		WDR5_HUMAN (658-772): 3.81e-36: 141: 21.37
+	Ce
		590577 HM06_CAEEL (79-394): 4.72e-45: 163: 37.58		WDR51_CAEEL (658-772): 1.53e-30: 126: 18.80
+	Mm
		590280 PO5F1_MOUSE (72-422): 5.45e-50: 176: 31.48		GBB1_MOUSE (689-772): 7.32e-15: 78.6: 17.65
+	Hs
		1080558 ZFHX3_HUMAN (276-362): 3.29e-11: 68.2: 25.29		SNR40_HUMAN (510-690): 4.15e-10: 64.3: 27.98