HitPredict

Interactor 1: INSR (P09208)
Insulin-like receptor (dIR) (dInr) (EC 2.7.10.1) (Insulin receptor homolog) (dIRH) (Receptor protein-tyrosine kinase InR) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1 (Insulin-like receptor subunit beta 170 kDa form) (beta170); Insulin-like receptor subunit beta 2 (Insulin-like receptor subunit beta 90 kDa form) (beta90); 60 kDa C-terminal fragment (Insulin-like receptor free C-terminus)]
Gene: InR

Interactor 2: LAR (P16621)
Tyrosine-protein phosphatase Lar (EC 3.1.3.48) (Protein-tyrosine-phosphate phosphohydrolase) (dLAR)
Gene: LAR

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 21931847, 31784462
Identification Methods enzymatic study, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase, Recep_L_domain~fn3
Common GO terms GO:0007399 - nervous system development
GO:0007411 - axon guidance
GO:0030424 - axon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2144
Dm

1 2029
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024