Interactor 1: INSR (P09208)
Insulin-like receptor (dIR) (dInr) (EC 2.7.10.1) (Insulin receptor homolog) (dIRH) (Receptor protein-tyrosine kinase InR) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1 (Insulin-like receptor subunit beta 170 kDa form) (beta170); Insulin-like receptor subunit beta 2 (Insulin-like receptor subunit beta 90 kDa form) (beta90); 60 kDa C-terminal fragment (Insulin-like receptor free C-terminus)]
Gene: InR

Interactor 2: PTP99 (P35832)
Tyrosine-protein phosphatase 99A (EC 3.1.3.48) (Receptor-linked protein-tyrosine phosphatase 99A) (DPTP99A)
Gene: Ptp99A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 21931847
Identification Methods enzymatic study, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase, Recep_L_domain~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0030424 - axon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Dm

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Last updated: 15 Jul 2024