HitPredict

Interactor 1: RU1C (P09234)
U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C)
Gene: SNRPC

Interactor 2: TRA2B (P62995)
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)
Gene: TRA2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005681 - spliceosomal complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 159 Hs			1 288
+	Hs
		448643 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		TRA2A_HUMAN (1-237): 9.33e-36: 131: 62.06
+	Hs
		448828 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		RBM22_HUMAN (2-287): 6.71e-33: 126: 15.91
+	Hs
		448855 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		PPIE_HUMAN (118-201): 7.87e-27: 107: 36.91
+	Hs
		448653 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		RBM39_HUMAN (15-248): 3.58e-18: 86.1: 21.83
+	Hs
		448558 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		TIA1_HUMAN (113-248): 8.75e-18: 84.1: 18.42
+	Hs
		448651 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		HNRPD_HUMAN (106-178): 6.05e-11: 64: 26.03
+	Sc
		376932 RU1C_YEAST (1-52): 1.39e-21: 88.7: 44.23		PABP_YEAST (98-206): 7.98e-20: 91.1: 19.27