HitPredict

Interactor 1: RU1C (P09234)
U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C)
Gene: SNRPC

Interactor 2: RSMN (P63162)
Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein)
Gene: SNRPN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~zf-U1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0005685 - U1 snRNP and 1 others more... GO:0071004 - U2-type prespliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 159 Hs			1 240
+	Hs
		448542 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		RSMB_HUMAN (1-168): 1.09e-43: 148: 96.43
+	Hs
		123834 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		SPT5H_HUMAN (100-228): 4.97e-25: 105: 17.69
+	Hs
		297810 RU1C_HUMAN (1-159): 4.69e-58: 180: 100.00		K0754_HUMAN (49-240): 8.86e-22: 95.8: 14.04
+	Sc
		766957 RU1C_YEAST (1-52): 1.39e-21: 88.7: 44.23		RSMB_YEAST (1-165): 2.64e-36: 128: 28.72