Interactor 1: GROA (P09341)
Growth-regulated alpha protein (C-X-C motif chemokine 1) (GRO-alpha(1-73)) (Melanoma growth stimulatory activity) (MGSA) (Neutrophil-activating protein 3) (NAP-3) [Cleaved into: GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73)]
Gene: CXCL1

Interactor 2: CXCR1 (P25024)
C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)
Gene: CXCR1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9195914
Identification Methods biochemical
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~IL8
Common GO terms GO:0007186 - G protein-coupled receptor signaling pathway
GO:0030593 - neutrophil chemotaxis
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 107
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024