HitPredict

Interactor 1: GRPE (P09372)
Protein GrpE (HSP-70 cofactor) (HSP24) (Heat shock protein B25.3)
Gene: GRPE

Interactor 2: CH60 (P0A6F5)
Chaperonin GroEL (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin-60) (Cpn60) (GroEL protein)
Gene: groEL

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	24561554, 10647006, 19402753, 15690043
Identification Methods	two hybrid, coimmunoprecipitation, tandem affinity purification, pull down, two hybrid array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0009408 - response to heat GO:0051082 - unfolded protein binding GO:0051085 - chaperone cofactor-dependent protein refolding GO:0051087 - protein-folding chaperone binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 197 Ec			1 548
+	Sc
		588056 GRPE_YEAST (23-196): 3.22e-57: 181: 30.94		HSP60_YEAST (4-523): 2.11e-166: 485: 54.20