HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 1480
+	Hs
		528500 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529457 PPL13_HUMAN (1-132): 2.72e-43: 140: 18.57		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		398162 LEG2_HUMAN (1-135): 3.89e-42: 137: 42.22		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528846 LEG4_HUMAN (5-134): 3.8e-36: 127: 26.28		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		119130 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		572294 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70
+	Hs
		179342 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		MRP4_HUMAN (5-647): 2.25e-59: 227: 15.67
+	Hs
		572423 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		MRP2_HUMAN (798-1466): 4.31e-56: 217: 15.74
+	Hs
		121117 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70
+	Hs
		119206 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70
+	Hs
		121056 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		MRP4_HUMAN (5-647): 2.25e-59: 227: 15.67
+	Hs
		119023 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		MRP4_HUMAN (5-647): 2.25e-59: 227: 15.67
+	Hs
		179360 LEG9B_HUMAN (10-133): 1.12e-34: 124: 30.71		MRP4_HUMAN (5-647): 2.25e-59: 227: 15.67
+	Hs
		179365 LEG9C_HUMAN (10-133): 7.56e-35: 124: 30.71		MRP4_HUMAN (5-647): 2.25e-59: 227: 15.67
+	Hs
		119468 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		MRP2_HUMAN (798-1466): 4.31e-56: 217: 15.74
+	Hs
		119024 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		MRP5_HUMAN (774-1479): 5.77e-53: 207: 13.26