HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome GO:0098609 - cell-cell adhesion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 742
+	Hs
		555071 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		121100 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		CD44_HUMAN (1-742): 0: 610: 100.00
+	Hs
		119143 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		CD44_HUMAN (1-742): 0: 610: 100.00
+	Mm
		139221 LEG9_MOUSE (5-133): 5.75e-38: 133: 27.21		CD44_MOUSE (1-742): 0: 540: 65.90
+	Hs
		449171 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86
+	Hs
		530369 LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58		CSPG2_HUMAN (13-660): 1.02e-75: 269: 14.86