HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: LEUK (P16150)
Leukosialin (GPL115) (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)]
Gene: SPN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	10490978, 33961781, 19635795, 17015718
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0031295 - T cell costimulation GO:0070062 - extracellular exosome
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 400
+	Hs
		556495 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		LEUK_HUMAN (1-400): 3.42e-119: 353: 100.00
+	Hs
		121101 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		LEUK_HUMAN (1-400): 3.42e-119: 353: 100.00