HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: PECA1 (P16284)
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
Gene: PECAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 32814053
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070062 - extracellular exosome GO:0098609 - cell-cell adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 738
+	Hs
		449332 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		NRCAM_HUMAN (27-737): 1.58e-58: 217: 11.01
+	Hs
		449281 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Hs
		572370 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Hs
		814965 LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Hs
		131991 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		NCHL1_HUMAN (345-736): 3.48e-36: 149: 14.55
+	Hs
		449205 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		L1CAM_HUMAN (320-735): 7.5e-36: 148: 12.88
+	Hs
		449252 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTK7_HUMAN (8-235): 3.28e-27: 120: 12.45
+	Hs
		449185 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75