HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043236 - laminin binding GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 135 Hs			1 1181
+	Hs
		566849 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		121102 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		449228 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA1_HUMAN (1-1169): 0: 1134: 38.84
+	Hs
		572330 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		ITA1_HUMAN (1-1169): 0: 1134: 38.84
+	Hs
		506097 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		ITAM_HUMAN (18-1169): 0: 983: 26.19
+	Hs
		121106 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		ITAL_HUMAN (12-1169): 0: 860: 24.61
+	Hs
		449196 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32
+	Hs
		449190 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		449257 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA7_HUMAN (5-512): 4.56e-57: 218: 17.52
+	Hs
		449225 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA8_HUMAN (2-546): 1.48e-53: 206: 17.24
+	Hs
		449172 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73
+	Hs
		419138 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITAV_HUMAN (27-513): 6.67e-48: 188: 15.25
+	Hs
		443022 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		449259 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		ITA9_HUMAN (26-513): 1.33e-45: 181: 16.37
+	Hs
		443032 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		121095 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73
+	Hs
		443090 LEG12_HUMAN (6-134): 8.15e-40: 137: 24.64		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		121078 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		ITAV_HUMAN (27-513): 6.67e-48: 188: 15.25
+	Hs
		121084 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Mm
		139224 LEG9_MOUSE (5-133): 5.75e-38: 133: 27.21		ITA2B_MOUSE (4-282): 3.44e-23: 109: 14.67