HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 18838383
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 135 Hs			1 1997
+	Hs
		449184 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRA_HUMAN (1687-1966): 2.17e-103: 353: 35.23
+	Hs
		572277 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRA_HUMAN (1687-1966): 2.17e-103: 353: 35.23
+	Hs
		449192 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRD_HUMAN (902-1709): 1.7e-69: 262: 12.33
+	Hs
		449281 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		SDK2_HUMAN (3-473): 6e-50: 198: 14.84
+	Hs
		572370 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		SDK2_HUMAN (3-473): 6e-50: 198: 14.84
+	Hs
		362725 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13
+	Hs
		362790 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13
+	Hs
		362931 LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58		FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13
+	Hs
		441165 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRC_HUMAN (1703-1975): 3.32e-25: 117: 27.67
+	Hs
		449194 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96
+	Hs
		449193 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRG_HUMAN (1727-1968): 6.3e-23: 109: 29.60
+	Hs
		572368 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRO_HUMAN (41-479): 4.06e-24: 113: 14.46
+	Hs
		572282 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96
+	Hs
		572281 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRG_HUMAN (1727-1968): 6.3e-23: 109: 29.60
+	Hs
		449306 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		SDK1_HUMAN (4-212): 1.75e-18: 95.1: 15.35
+	Hs
		449248 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRJ_HUMAN (1245-1617): 2.86e-16: 87.8: 15.75
+	Hs
		572394 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		SDK1_HUMAN (4-212): 1.75e-18: 95.1: 15.35
+	Hs
		449266 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTPRK_HUMAN (262-866): 9.73e-16: 85.8: 10.10
+	Hs
		572351 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRJ_HUMAN (1245-1617): 2.86e-16: 87.8: 15.75
+	Hs
		572363 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		PTPRK_HUMAN (262-866): 9.73e-16: 85.8: 10.10