HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18288482
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0042981 - regulation of apoptotic process GO:0043065 - positive regulation of apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 335
+	Hs
		572287 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		TNR6_HUMAN (1-335): 2.61e-113: 333: 100.00
+	Hs
		155877 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		TR10C_HUMAN (43-233): 6.82e-33: 124: 19.19
+	Hs
		172634 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		LAMA5_HUMAN (27-237): 5.83e-25: 108: 17.76
+	Hs
		449272 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86
+	Hs
		572366 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86
+	Hs
		814958 LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86
+	Hs
		121163 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86
+	Hs
		119397 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		LAMA4_HUMAN (34-233): 2.06e-14: 76.5: 13.86