HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: CD166 (Q13740)
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Gene: ALCAM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.684

Property	Details
Experiments	33961781, 28514442, 24945728
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, competition binding, enzyme linked immunosorbent assay, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 583
+	Hs
		572356 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		121151 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		119364 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		1045045 LEG9B_HUMAN (10-133): 1.12e-34: 124: 30.71		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		449219 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		572314 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		121126 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		572445 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		CADM1_HUMAN (259-493): 5.61e-20: 94.9: 19.64
+	Hs
		449252 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTK7_HUMAN (16-146): 1.62e-10: 66.3: 13.74