HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 135 Hs			1 1150
+	Hs
		572474 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		121226 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		119555 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		572481 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		449398 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		121232 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		572490 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		119565 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		815062 LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		121236 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		572325 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		121133 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		119282 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		572442 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		S12A9_HUMAN (184-977): 1.39e-156: 492: 25.06
+	Hs
		121209 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		S12A9_HUMAN (184-977): 1.39e-156: 492: 25.06
+	Hs
		119512 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		S12A9_HUMAN (184-977): 1.39e-156: 492: 25.06
+	Hs
		572323 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		119269 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		119196 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		119332 LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08