Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 29721183
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box, HMG_box~HMG_box_2, HMG_box_2~HMG_box_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000400 - four-way junction DNA binding
GO:0000405 - bubble DNA binding
GO:0000793 - condensed chromosome
GO:0000976 - transcription cis-regulatory region binding
and 85 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 215
Hs

1 215
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Last updated: 15 Jul 2024