HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003690 - double-stranded DNA binding GO:0003697 - single-stranded DNA binding GO:0003723 - RNA binding GO:0005576 - extracellular region GO:0005634 - nucleus and 1 others more... GO:0031175 - neuron projection development
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 758
+	Hs
		496347 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		175742 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496921 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496854 TFAM_HUMAN (95-186): 2.95e-09: 57.1: 17.39		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		152684 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		152610 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		152619 SOX10_HUMAN (4-98): 1.86e-21: 93.2: 14.74		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		152690 SOX17_HUMAN (10-90): 2.4e-12: 67.1: 19.75		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		1243837 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		818266 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Ce
		136646 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		RPB1_CAEEL (82-426): 9.08e-11: 68: 14.12
+	Hs
		1243843 SOX17_HUMAN (10-90): 2.4e-12: 67.1: 19.75		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91