HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22623428
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0006954 - inflammatory response GO:0009986 - cell surface
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 739
+	Hs
		581447 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581697 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581677 TFAM_HUMAN (95-186): 2.95e-09: 57.1: 17.39		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		449779 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		996908 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		ROBO2_HUMAN (19-529): 4.08e-16: 85: 14.59