HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29721183
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 391
+	Hs
		745137 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Mm
		857305 HMGB1_MOUSE (1-174): 9.92e-46: 152: 100.00		TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18
+	Hs
		996959 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23
+	Hs
		516365 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27
+	Hs
		745272 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		680429 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81
+	Dm
		1098043 DICH_DROME (7-101): 3.34e-27: 108: 24.21		Q9VBQ1_DROME (3-88): 3.91e-19: 91: 27.91
+	Hs
		818011 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89
+	Hs
		817926 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		TIAR_HUMAN (1-344): 2.52e-18: 87.6: 15.23
+	Mm
		639837 UBF1_MOUSE (49-203): 2.84e-09: 58.2: 20.25		TIAR_MOUSE (1-344): 2.31e-15: 78.7: 15.70