HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36585612, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 679
+	Hs
		449509 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		175743 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Ce
		136645 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		HSP6_CAEEL (48-677): 0: 922: 77.18
+	Hs
		503969 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		297452 TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		751532 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		GRP75_HUMAN (1-679): 0: 873: 100.00
+	Hs
		504610 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		503899 TFAM_HUMAN (95-186): 2.95e-09: 57.1: 17.39		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		751782 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		GRP75_HUMAN (1-679): 0: 873: 100.00
+	Hs
		871744 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		HSP72_HUMAN (50-653): 0: 868: 49.11
+	Hs
		449508 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		BIP_HUMAN (53-677): 0: 566: 50.55
+	Hs
		502452 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		BIP_HUMAN (53-677): 0: 566: 50.55