HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: RAD50 (P12753)
DNA repair protein RAD50 (EC 3.6.-.-) (153 kDa protein)
Gene: RAD50

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	16554755, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 1312
+	Sc
		493049 HSP72_YEAST (1-649): 0: 941: 78.89		RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00
+	Sc
		490162 HSP71_YEAST (1-649): 0: 939: 79.35		RAD50_YEAST (1-1312): 1.86e-103: 360: 100.00
+	Hs
		504509 HSP7C_HUMAN (2-649): 0: 946: 72.53		RAD50_HUMAN (1-1312): 2e-86: 310: 25.28
+	Hs
		504086 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMC1A_HUMAN (1-1287): 1.38e-59: 226: 11.78
+	Hs
		64578 HSP7C_HUMAN (2-649): 0: 946: 72.53		MYH7B_HUMAN (254-1211): 4.86e-30: 132: 10.10
+	Hs
		503376 HSP7C_HUMAN (2-649): 0: 946: 72.53		DESP_HUMAN (179-757): 9.93e-12: 72.3: 11.71
+	Sc
		493298 HSP72_YEAST (1-649): 0: 941: 78.89		USO1_YEAST (230-1038): 2.47e-09: 64.3: 20.75
+	Sc
		490455 HSP71_YEAST (1-649): 0: 939: 79.35		USO1_YEAST (230-1038): 2.47e-09: 64.3: 20.75