HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: MAS5 (P25491)
Mitochondrial protein import protein MAS5 (Yeast dnaJ protein 1)
Gene: YDJ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	11320326, 19536198
Identification Methods	x-ray crystallography, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042026 - protein refolding and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 649 Sc			1 409
+	Hs
		681341 HS71L_HUMAN (2-649): 0: 958: 70.06		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		564015 HSP76_HUMAN (4-649): 0: 950: 70.43		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		503527 HSP7C_HUMAN (2-649): 0: 946: 72.53		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		564136 HSP76_HUMAN (4-649): 0: 950: 70.43		DNJA4_HUMAN (1-408): 3.64e-148: 427: 46.10
+	Hs
		243312 HS71L_HUMAN (2-649): 0: 958: 70.06		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Hs
		243284 HSP76_HUMAN (4-649): 0: 950: 70.43		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Hs
		243275 HSP7C_HUMAN (2-649): 0: 946: 72.53		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Hs
		279280 HS71L_HUMAN (2-649): 0: 958: 70.06		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		714049 HS71L_HUMAN (2-649): 0: 958: 70.06		DNJA3_HUMAN (2-398): 1.93e-117: 352: 25.00
+	Hs
		714088 HS71L_HUMAN (2-649): 0: 958: 70.06		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Hs
		279274 HSP76_HUMAN (4-649): 0: 950: 70.43		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		564203 HSP76_HUMAN (4-649): 0: 950: 70.43		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Hs
		279272 HSP7C_HUMAN (2-649): 0: 946: 72.53		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		504564 HSP7C_HUMAN (2-649): 0: 946: 72.53		DNJA3_HUMAN (2-398): 1.93e-117: 352: 25.00
+	Hs
		504901 HSP7C_HUMAN (2-649): 0: 946: 72.53		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Sc
		450143 HSP73_YEAST (1-649): 0: 948: 100.00		APJ1_YEAST (1-353): 1.92e-68: 227: 35.19
+	Hs
		714087 HS71L_HUMAN (2-649): 0: 958: 70.06		DJB11_HUMAN (7-349): 1.79e-48: 170: 36.60
+	Hs
		564202 HSP76_HUMAN (4-649): 0: 950: 70.43		DJB11_HUMAN (7-349): 1.79e-48: 170: 36.60
+	Sc
		493271 HSP72_YEAST (1-649): 0: 941: 78.89		SCJ1_YEAST (7-350): 5.15e-51: 177: 38.95
+	Hs
		504897 HSP7C_HUMAN (2-649): 0: 946: 72.53		DJB11_HUMAN (7-349): 1.79e-48: 170: 36.60