HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: STH1 (P32597)
Nuclear protein STH1/NPS1 (EC 3.6.4.12) (ATP-dependent helicase STH1) (Chromatin structure-remodeling complex protein STH1) (SNF2 homolog)
Gene: STH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 649 Sc			1 1359
+	Sc
		493493 HSP72_YEAST (1-649): 0: 941: 78.89		STH1_YEAST (1-1359): 0: 950: 100.00
+	Sc
		490681 HSP71_YEAST (1-649): 0: 939: 79.35		STH1_YEAST (1-1359): 0: 950: 100.00
+	Sc
		493206 HSP72_YEAST (1-649): 0: 941: 78.89		SNF2_YEAST (19-1357): 0: 733: 42.05
+	Sc
		490344 HSP71_YEAST (1-649): 0: 939: 79.35		SNF2_YEAST (19-1357): 0: 733: 42.05
+	Sc
		450221 HSP73_YEAST (1-649): 0: 948: 100.00		ISW2_YEAST (334-991): 0: 684: 39.40
+	Sc
		495184 HSP72_YEAST (1-649): 0: 941: 78.89		ISW2_YEAST (334-991): 0: 684: 39.40
+	Sc
		605391 HSP74_YEAST (1-649): 0: 924: 86.75		ISW2_YEAST (334-991): 0: 684: 39.40
+	Hs
		229290 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMCA5_HUMAN (366-1266): 0: 634: 30.99
+	Hs
		503984 HSP7C_HUMAN (2-649): 0: 946: 72.53		CHD3_HUMAN (295-1281): 0: 630: 25.58
+	Hs
		713973 HS71L_HUMAN (2-649): 0: 958: 70.06		CHD4_HUMAN (295-1253): 0: 614: 25.95
+	Hs
		871693 HSP72_HUMAN (2-610): 0: 927: 74.63		CHD5_HUMAN (266-1288): 0: 642: 23.94
+	Hs
		504094 HSP7C_HUMAN (2-649): 0: 946: 72.53		CHD4_HUMAN (295-1253): 0: 614: 25.95
+	Sc
		450019 HSP73_YEAST (1-649): 0: 948: 100.00		ISW1_YEAST (439-958): 1.81e-120: 405: 46.07
+	Sc
		493764 HSP72_YEAST (1-649): 0: 941: 78.89		ISW1_YEAST (439-958): 1.81e-120: 405: 46.07
+	Sc
		490987 HSP71_YEAST (1-649): 0: 939: 79.35		ISW1_YEAST (439-958): 1.81e-120: 405: 46.07
+	Sc
		449977 HSP73_YEAST (1-649): 0: 948: 100.00		CHD1_YEAST (456-990): 1.42e-114: 395: 41.79
+	Sc
		493508 HSP72_YEAST (1-649): 0: 941: 78.89		CHD1_YEAST (456-990): 1.42e-114: 395: 41.79
+	Sc
		490702 HSP71_YEAST (1-649): 0: 939: 79.35		CHD1_YEAST (456-990): 1.42e-114: 395: 41.79
+	Hs
		503711 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMCA2_HUMAN (1085-1358): 1.81e-25: 117: 13.73
+	Dm
		505047 HSP7D_DROME (2-649): 0: 938: 72.53		BRM_DROME (1014-1357): 7.67e-23: 108: 14.83