HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: SMC1 (P32908)
Structural maintenance of chromosomes protein 1 (DA-box protein SMC1)
Gene: SMC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0016887 - ATP hydrolysis activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 1225
+	Sc
		493545 HSP72_YEAST (1-649): 0: 941: 78.89		SMC1_YEAST (1-1225): 2.49e-103: 357: 100.00
+	Sc
		490744 HSP71_YEAST (1-649): 0: 939: 79.35		SMC1_YEAST (1-1225): 2.49e-103: 357: 100.00
+	Hs
		504086 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMC1A_HUMAN (1-1225): 2.94e-92: 325: 26.86
+	Hs
		504825 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMC4_HUMAN (4-1220): 3.9e-85: 305: 19.46
+	Hs
		311464 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMC2_HUMAN (3-1217): 6.93e-75: 273: 18.17
+	Sc
		493970 HSP72_YEAST (1-649): 0: 941: 78.89		SMC2_YEAST (3-1216): 3.11e-76: 277: 16.23
+	Hs
		504974 HSP7C_HUMAN (2-649): 0: 946: 72.53		SMC3_HUMAN (3-1222): 4.26e-74: 271: 16.89
+	Sc
		491224 HSP71_YEAST (1-649): 0: 939: 79.35		SMC2_YEAST (3-1216): 3.11e-76: 277: 16.23
+	Sc
		494321 HSP72_YEAST (1-649): 0: 941: 78.89		SMC3_YEAST (3-1221): 2.09e-67: 251: 15.88