HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: RPN14 (P53196)
26S proteasome regulatory subunit RPN14 (Proteasome non-ATPase subunit 14)
Gene: RPN14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 417
+	Hs
		714020 HS71L_HUMAN (2-649): 0: 958: 70.06		POC1A_HUMAN (123-414): 4.96e-65: 215: 15.02
+	Hs
		564125 HSP76_HUMAN (4-649): 0: 950: 70.43		POC1A_HUMAN (123-414): 4.96e-65: 215: 15.02
+	Hs
		503614 HSP7C_HUMAN (2-649): 0: 946: 72.53		LIS1_HUMAN (132-416): 4.29e-65: 215: 16.34
+	Hs
		504412 HSP7C_HUMAN (2-649): 0: 946: 72.53		POC1A_HUMAN (123-414): 4.96e-65: 215: 15.02
+	Hs
		503743 HSP7C_HUMAN (2-649): 0: 946: 72.53		COPA_HUMAN (129-415): 2.05e-52: 190: 11.15
+	Sc
		495354 HSP72_YEAST (1-649): 0: 941: 78.89		PRP46_YEAST (64-366): 5.58e-45: 163: 15.06
+	Sc
		492897 HSP71_YEAST (1-649): 0: 939: 79.35		PRP46_YEAST (64-366): 5.58e-45: 163: 15.06
+	Hs
		503817 HSP7C_HUMAN (2-649): 0: 946: 72.53		WDR5_HUMAN (217-415): 1.93e-39: 145: 11.50
+	Hs
		504344 HSP7C_HUMAN (2-649): 0: 946: 72.53		WDR5B_HUMAN (208-413): 9.8e-38: 140: 11.59
+	Hs
		209386 HSP7C_HUMAN (2-649): 0: 946: 72.53		PLRG1_HUMAN (41-271): 3.95e-35: 137: 18.46
+	Sc
		450129 HSP73_YEAST (1-649): 0: 948: 100.00		COPA_YEAST (3-403): 1.28e-29: 123: 7.57
+	Sc
		494582 HSP72_YEAST (1-649): 0: 941: 78.89		COPA_YEAST (3-403): 1.28e-29: 123: 7.57
+	Sc
		491987 HSP71_YEAST (1-649): 0: 939: 79.35		COPA_YEAST (3-403): 1.28e-29: 123: 7.57
+	Sc
		605373 HSP74_YEAST (1-649): 0: 924: 86.75		COPA_YEAST (3-403): 1.28e-29: 123: 7.57
+	Hs
		504523 HSP7C_HUMAN (2-649): 0: 946: 72.53		FBXW7_HUMAN (316-416): 1.38e-10: 65.1: 14.71
+	Dm
		505116 HSP7D_DROME (2-649): 0: 938: 72.53		FBXW7_DROME (316-414): 1.2e-11: 68.9: 14.00