HitPredict

Interactor 1: ACHA4 (P09483)
Neuronal acetylcholine receptor subunit alpha-4
Gene: Chrna4

Interactor 2: ACHA5 (P20420)
Neuronal acetylcholine receptor subunit alpha-5
Gene: Chrna5

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 20566638
Identification Methods cosedimentation through density gradient, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0007271 - synaptic transmission, cholinergic
GO:0015464 - acetylcholine receptor activity
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
and 12 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 630
Rn

1 452
+ Mm
+ Mm
+ Rn
+ Hs
+ Gg
+ Rn
+ Hs
+ Hs
+ Hs
+ Gg
+ Gg
+ Gg
+ Hs
+ Gg
+ Gg
+ Hs
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024