Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 30021884
Identification Methods proximity labelling technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Tropomyosin
Common GO terms GO:0005829 - cytosol
GO:0005884 - actin filament
GO:0007015 - actin filament organization
GO:0030017 - sarcomere
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 284
Hs

1 377
+ Dm
+ Hs
+ Oc
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024