HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0003779 - actin binding GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 457
+	Hs
		419055 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		434438 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		110806 H7BYY1_HUMAN (41-284): 8.14e-35: 127: 70.49		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		932058 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Mm
		886037 TPM1_MOUSE (1-284): 1.72e-44: 153: 99.65		PDLI5_MOUSE (1-282): 2.11e-28: 120: 24.47
+	Mm
		886046 TPM2_MOUSE (1-284): 2.06e-38: 138: 85.92		PDLI5_MOUSE (1-282): 2.11e-28: 120: 24.47
+	Hs
		434422 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		PDLI5_HUMAN (1-282): 6.17e-28: 118: 24.82
+	Hs
		434336 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		ZN250_HUMAN (362-457): 4.28e-23: 103: 6.25
+	Hs
		418964 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1076422 Q5VU62_HUMAN (127-284): 3.37e-44: 149: 90.51		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		932007 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42