HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.922

The method score is based on:

Property	Details
Experiments	26496610, 35271311, 21411634, 34079125, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Clathrin~Clathrin_lg_ch
Common GO terms	GO:0005198 - structural molecule activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0030118 - clathrin coat and 4 others more... GO:0030130 - clathrin coat of trans-Golgi network vesicle GO:0030132 - clathrin coat of coated pit GO:0045334 - clathrin-coated endocytic vesicle GO:0072583 - clathrin-dependent endocytosis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	229
Hs

1	1675

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024