HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030125 - clathrin vesicle coat GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 625
+	Hs
		451438 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		451628 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Rn
		291385 CLCA_RAT (13-227): 8.1e-98: 286: 59.91		EPN1_RAT (8-529): 1.01e-68: 235: 24.63
+	Hs
		451762 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		307497 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		307498 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		203201 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29
+	Hs
		203202 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29