HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: AAK1 (Q2M2I8)
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)
Gene: AAK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 961
+	Hs
		451455 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AAK1_HUMAN (1-961): 0: 720: 100.00
+	Hs
		451576 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		BMP2K_HUMAN (37-767): 7.31e-125: 409: 47.28
+	Hs
		451742 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		BMP2K_HUMAN (37-767): 7.31e-125: 409: 47.28
+	Hs
		451639 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		MARK3_HUMAN (2-692): 2.26e-119: 383: 14.89
+	Hs
		161612 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		GAK_HUMAN (18-309): 7.18e-44: 175: 38.33
+	Hs
		161613 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		GAK_HUMAN (18-309): 7.18e-44: 175: 38.33
+	Hs
		274172 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		STK16_HUMAN (52-304): 4.56e-26: 111: 30.42