HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: WNK3 (Q9BYP7)
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)
Gene: WNK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 32707033
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 1800
+	Hs
		451550 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		WNK3_HUMAN (1-1800): 0: 1277: 100.00
+	Hs
		254435 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		ROCK2_HUMAN (56-1221): 1.1e-147: 494: 12.41
+	Hs
		451639 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		MARK3_HUMAN (96-784): 3.19e-131: 430: 15.58
+	Hs
		451616 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		WNK2_HUMAN (1-719): 2.5e-112: 400: 49.73
+	Hs
		99456 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		F5GWT4_HUMAN (666-1798): 1.79e-114: 406: 18.51
+	Hs
		451559 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		WNK1_HUMAN (27-1637): 1.09e-101: 366: 26.62
+	Hs
		451733 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		WNK1_HUMAN (27-1637): 1.09e-101: 366: 26.62
+	Hs
		451689 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		OBSCN_HUMAN (110-421): 9.24e-45: 181: 20.63
+	Hs
		164681 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		MAST4_HUMAN (444-1526): 2.28e-10: 68.3: 9.61