HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1106 Hs			1 540
+	Hs
		452421 PGFRB_HUMAN (1-1106): 0: 795: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		557115 PGFRA_HUMAN (3-1106): 0: 716: 42.48		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		452485 PGFRB_HUMAN (1-1106): 0: 795: 100.00		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Ce
		1014310 EGL15_CAEEL (11-1064): 1.41e-153: 486: 16.68		SNT1_CAEEL (84-538): 8.28e-114: 346: 37.64
+	Hs
		507981 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		507990 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		280015 KIT_HUMAN (3-1003): 0: 601: 29.99		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		609274 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		609282 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		729276 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		1081612 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1081620 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		607960 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		1021503 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		169214 MUSK_HUMAN (120-966): 1.11e-145: 460: 16.48		PZRN3_HUMAN (7-198): 8.64e-16: 83: 14.35
+	Hs
		607963 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		508210 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		601598 FGFR2_HUMAN (9-326): 2.34e-58: 218: 11.51		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		609552 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		280018 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07