HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1106 Hs			1 505
+	Hs
		437821 PGFRB_HUMAN (1-1106): 0: 795: 100.00		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431450 PGFRB_HUMAN (1-1106): 0: 795: 100.00		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		499223 KIT_HUMAN (3-1003): 0: 601: 29.99		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		431600 FLT3_HUMAN (21-1008): 7e-168: 522: 26.73		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		169160 MUSK_HUMAN (120-966): 1.11e-145: 460: 16.48		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		169159 MUSK_HUMAN (120-966): 1.11e-145: 460: 16.48		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		438114 MERTK_HUMAN (120-967): 1.8e-135: 437: 16.54		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		438205 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431788 MERTK_HUMAN (120-967): 1.8e-135: 437: 16.54		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		431892 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Ce
		1014308 EGL15_CAEEL (11-1064): 1.41e-153: 486: 16.68		ENPL1_CAEEL (1-504): 0: 562: 34.09
+	Hs
		431749 ROR1_HUMAN (219-1095): 2.41e-113: 376: 14.94		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		538251 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		437838 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431472 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		437897 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		169183 MUSK_HUMAN (120-966): 1.11e-145: 460: 16.48		Q6PK50_HUMAN (1-301): 1.17e-138: 405: 80.26
+	Hs
		431536 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		431595 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		508043 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87