HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: FARP1 (Q9Y4F1)
FERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)
Gene: FARP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr, PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1106 Hs			1 1045
+	Hs
		557299 PGFRA_HUMAN (3-1106): 0: 716: 42.48		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		508287 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		299238 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		FARP2_HUMAN (1-1040): 0: 780: 53.19
+	Hs
		452448 PGFRB_HUMAN (1-1106): 0: 795: 100.00		FGD6_HUMAN (495-915): 9.38e-35: 146: 28.21
+	Hs
		719722 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25
+	Hs
		507828 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		508209 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		E41LA_HUMAN (37-584): 4.2e-99: 329: 23.37
+	Hs
		507885 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25
+	Hs
		505551 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		EPB41_HUMAN (3-547): 3.71e-115: 378: 29.21
+	Hs
		609192 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25
+	Mm
		1206834 PTK7_MOUSE (218-494): 7.39e-27: 120: 17.07		E41L3_MOUSE (35-578): 1.64e-122: 399: 28.17
+	Dm
		112241 M9MRE1_DROME (32-503): 7e-43: 173: 16.67		Q9W0R3_DROME (5-546): 7.15e-101: 341: 28.32
+	Hs
		719673 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25
+	Hs
		674528 UFO_HUMAN (5-330): 1.39e-13: 77.6: 13.03		E41L1_HUMAN (20-550): 6.05e-122: 396: 29.16
+	Hs
		674532 UFO_HUMAN (5-330): 1.39e-13: 77.6: 13.03		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		204618 UFO_HUMAN (5-330): 1.39e-13: 77.6: 13.03		E41L2_HUMAN (3-549): 7.69e-117: 386: 29.58
+	Hs
		505564 UFO_HUMAN (5-330): 1.39e-13: 77.6: 13.03		EPB41_HUMAN (3-547): 3.71e-115: 378: 29.21
+	Hs
		607939 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		FGD1_HUMAN (317-1040): 1.54e-101: 343: 18.94
+	Hs
		546928 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		607901 FGFR4_HUMAN (200-413): 5.32e-14: 78.7: 17.73		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25