HitPredict

Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1106 Hs			1 999
+	Hs
		738300 FLT3_HUMAN (21-1008): 7e-168: 522: 26.73		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1018377 MERTK_HUMAN (120-967): 1.8e-135: 437: 16.54		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1081658 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		445887 ROS1_HUMAN (118-1073): 2.6e-112: 388: 16.99		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1081553 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		968353 ROR1_HUMAN (219-1095): 2.41e-113: 376: 14.94		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320862 NTRK3_HUMAN (65-966): 1.49e-133: 427: 16.58		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		320798 ROS1_HUMAN (118-1073): 2.6e-112: 388: 16.99		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		508291 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		572704 VGFR1_HUMAN (33-627): 2.19e-51: 200: 18.47		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		609631 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320803 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		729325 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320811 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		609191 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		320822 VGFR3_HUMAN (32-529): 2.63e-47: 187: 19.38		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		507880 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		507924 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		507836 FGFR1_HUMAN (218-720): 1.52e-70: 254: 20.44		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		503438 FGFR3_HUMAN (1-313): 7.09e-52: 198: 10.66		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42