HitPredict

Interactor 1: DLDH (P09622)
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
Gene: DLD

Interactor 2: AP1S2 (P56377)
AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)
Gene: AP1S2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	29128334
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 157
+	Hs
		452843 DLDH_HUMAN (1-509): 0: 543: 100.00		AP3S1_HUMAN (1-143): 5.8e-49: 157: 36.91
+	Mm
		139799 DLDH_MOUSE (1-509): 0: 537: 94.89		AP3S1_MOUSE (1-143): 5.8e-49: 157: 36.91
+	Hs
		452871 DLDH_HUMAN (1-509): 0: 543: 100.00		AP1M1_HUMAN (2-153): 2.63e-43: 149: 19.23
+	Hs
		452713 DLDH_HUMAN (1-509): 0: 543: 100.00		COPZ1_HUMAN (1-154): 4.68e-41: 137: 19.87