Interactor 1: DLDH (P09624)
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) (EC 1.8.1.4) (2-oxoglutarate dehydrogenase complex component E3) (OGDC-E3) (OGDHC subunit E3) (Alpha-ketoglutarate dehydrogenase complex subunit E3) (alpha-KGDHC subunit E3) (Dihydrolipoamide dehydrogenase) (Dihydrolipoamide:NAD(+) oxidoreductase) (Glycine decarboxylase complex subunit L) (GDC subunit L) (Lipoamide dehydrogenase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex E3 component) (PDC subunit E3) (PDH complex subunit E3)
Gene: LPD1

Interactor 2: ODPB (P32473)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (EC 1.2.4.1) (Pyruvate dehydrogenase complex component E1 beta) (PDHE1-B)
Gene: PDB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 11805826, 16429126, 32051233, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0042645 - mitochondrial nucleoid
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 499
Sc

1 366
+ Hs
+ Mm
+ Dm

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Last updated: 15 Jul 2024