HitPredict

Interactor 1: HXB7 (P09629)
Homeobox protein Hox-B7 (Homeobox protein HHO.C1) (Homeobox protein Hox-2C)
Gene: HOXB7

Interactor 2: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.597

Property	Details
Experiments	17308091
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 609
+	Hs
		523620 PDX1_HUMAN (13-217): 1.89e-36: 130: 27.88		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		446861 HXD4_HUMAN (3-197): 2.17e-35: 127: 34.60		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		446886 HXC4_HUMAN (3-211): 7.74e-31: 115: 32.16		XRCC6_HUMAN (1-609): 0: 666: 100.00
+	Hs
		453045 HXB7_HUMAN (1-208): 2.57e-59: 187: 100.00		XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77
+	Hs
		524850 PDX1_HUMAN (13-217): 1.89e-36: 130: 27.88		XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77
+	Hs
		446887 HXC4_HUMAN (3-211): 7.74e-31: 115: 32.16		XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77