HitPredict

Interactor 1: HXB7 (P09629)
Homeobox protein Hox-B7 (Homeobox protein HHO.C1) (Homeobox protein Hox-2C)
Gene: HOXB7

Interactor 2: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 444
+	Hs
		1151093 Q6FHY5_HUMAN (44-208): 4.03e-34: 125: 29.70		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		838086 MEOX2_HUMAN (44-208): 4.11e-34: 125: 29.70		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		446904 HXC4_HUMAN (3-211): 7.74e-31: 115: 32.16		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		829922 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		838087 MEOX2_HUMAN (44-208): 4.11e-34: 125: 29.70		Q7Z783_HUMAN (169-433): 7.64e-65: 213: 16.61
+	Hs
		208107 MEOX2_HUMAN (44-208): 4.11e-34: 125: 29.70		SPY2_HUMAN (169-433): 5.08e-63: 208: 16.61
+	Hs
		538731 HXB2_HUMAN (6-211): 1.46e-30: 116: 27.14		HOME1_HUMAN (11-343): 1.82e-65: 215: 12.89
+	Hs
		829924 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		Q7Z783_HUMAN (169-433): 7.64e-65: 213: 16.61
+	Hs
		208106 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		SPY2_HUMAN (169-433): 5.08e-63: 208: 16.61
+	Hs
		208331 MEOX2_HUMAN (44-208): 4.11e-34: 125: 29.70		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		208375 Q6FHY5_HUMAN (44-208): 4.03e-34: 125: 29.70		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		538744 HXB2_HUMAN (6-211): 1.46e-30: 116: 27.14		HOME2_HUMAN (11-230): 3.06e-59: 199: 12.11
+	Hs
		447297 HXB5_HUMAN (57-202): 8.06e-39: 136: 45.16		HOME3_HUMAN (11-333): 1.13e-50: 177: 11.68
+	Hs
		208329 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		830014 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		SPY4_HUMAN (168-435): 8.08e-54: 183: 14.97
+	Hs
		208414 MEOX2_HUMAN (44-208): 4.11e-34: 125: 29.70		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		208426 Q6FHY5_HUMAN (44-208): 4.03e-34: 125: 29.70		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		208413 HXA1_HUMAN (4-210): 4.88e-30: 115: 23.15		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79