HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 739
+	Hs
		581825 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		161960 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581428 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581561 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581837 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581722 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581824 MSI2H_HUMAN (2-91): 6.69e-16: 79.8: 35.56		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581713 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		581473 TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		1104165 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		162098 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		609973 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		590604 TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71		CD22_HUMAN (10-405): 1.39e-35: 146: 17.40
+	Hs
		1264791 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		1031405 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24