HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 246
+	Hs
		453256 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		453268 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		609795 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		852009 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		609804 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		453162 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		609720 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Mm
		935646 ROA0_MOUSE (9-186): 4.93e-59: 195: 59.55		1433F_MOUSE (4-244): 8.67e-108: 312: 75.51
+	Hs
		609792 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Mm
		935716 HNRDL_MOUSE (2-283): 2.78e-55: 185: 32.41		1433F_MOUSE (4-244): 8.67e-108: 312: 75.51
+	Mm
		910326 ROAA_MOUSE (2-100): 6.42e-18: 84.8: 29.29		1433E_MOUSE (3-243): 4.39e-144: 405: 65.43
+	Hs
		927029 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909516 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683319 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927003 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		646864 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		981998 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684027 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62