HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26186194, 17643375
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 644
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516424 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		1020249 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516689 PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516663 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516484 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516511 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Sc
		376562 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		PABP_YEAST (2-290): 4.28e-66: 228: 30.07
+	Hs
		609862 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Hs
		453138 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		453526 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		852134 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		1020259 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Hs
		474019 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		582288 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		1020306 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		680450 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53